Cervantes contra Lope is a TV movie portraying the confrontation between two of Europe's most famous literary writers, Miguel de Cervantes and Félix Lope de Vega, at the beginning of the 17th century. The subject is treated as a documentary. A TV crew from the 21st century is sent to Madrid in 1614 to interview Cervantes, Lope and people from their circle. The ''Quijote de Avellaneda'' has just been published and a bitter quarrel has broken out between the two literary geniuses. The TV Movie looks at the intrigue surrounding the identity of Avellaneda, while showing Cervantes and Lope as two brilliant individuals plagued with self-doubt and feelings of failure.